Results
| PMID | 23833592 |
| Gene Name | CRP |
| Condition | Endometriosis |
| Association |
Associated |
| Population size | 179 |
| Population details | 179 (90 with endometriosis, 89 without endometriosis) |
| Sex | Female |
| Other associated phenotypes |
Endometriosis |
|
Iran J Nurs Midwifery Res. 2012 Feb;17(2 Suppl 1):S115-9. Kianpour, Maryam| Nematbakhsh, Mehdi| Ahmadi, Sayad Mehdi Nursing and Midwifery Care Research Center, Department of Midwifery, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran. BACKGROUND: Endometriosis is defined as the existence of endometrial-like tissue outside the uterus. Diagnosis of endometriosis is a challenging theme. Despite the broad search for innovative laboratory tests and advances in imaging technologies, there are still no easy, non-invasive diagnostic tests available. Due to inflammatory process of endometriosis, still C-reactive protein (CRP) level may be the target of initial screening. The aim of this study was to investigate CRP levels as a marker of inflammatory process in serum and peritoneal fluid of patients with endometriosis. MATERIALS AND METHODS: In a case control study, 179 patients with endometriosis (N = 90) and without endometriosis (N = 89) were evaluated. The venous blood samples were obtained from all patients before laparoscopy and the peritoneal fluid samples were collected from pelvis before any manipulation. Student's t-test was applied to compare the parameters between two groups. FINDINGS: There was no significant difference between the CRP serum level in patients with endometriosis and infertile women without endometriosis. There was a significant difference in peritoneal level of CRP between case and control groups (p < 0.05). CONCLUSIONS: The findings suggested that measurement of this marker in patients' serum or plasma cannot be used to diagnose endometriosis. It is further recommended that a combination of different markers might be helpful in this regard that could be studied in future. Mesh Terms: DA2012/02/01 00:01 |
|